1. PIPC Chairman Tony Coelho: New Opportunities for Patient-Centered CER, click here to view the blog post.
2. PCORI Selects 30 Individuals, Small Groups for First "Pipeline to Proposal" Awards, click here to view the press release.
3. PCORI Blog: Evaluating PCORI’s Progress and Promise: A New Year’s Review, click here to view the blog post.
4. Pink Sheet: Drug-Related Topics Among PCORI Priorities For Large Pragmatic Clinical CER Trials, click here to view the article (subscription required).
5. AAMC Blog: New PCORI Methodology Report Offers Guidelines, Expectations for Comparative Effectiveness Research, click here to view the article.
6. MedPage Today: Blog: Evidence-Based Medicine and the Limitations of Research, click here to view the blog post.
In a new blog post, PIPC Chairman Tony Coelho discusses the opportunities and challenges ahead in raising awareness for the value of patient-centered comparative effectiveness research (CER). "As more CER results emerge, the approaches we take to communicating and apply results will be increasingly important," Chairman Coelho writes. “We’ll see a growing volume of CER in the years ahead, not only from PCORI but from many private sector researchers as well. And not only from clinical trials, but from new infrastructure like the Clinical Data Research Network that PCORI is creating.”
Chairman Coelho continues, “Patient-centered CER has the potential to improve health and increase the quality of health care decision-making. To reach this potential, it is imperative that dissemination of CER findings clearly communicate its limitations, as well as clear information about the subpopulations to which it applies, or does not apply… the continued emergence of new health care payment and delivery models [will] play a large role in shaping how CER results are applied, how patients are engaged in decision-making, and whether they gain access to the care they need. As these so-called ‘alternative payment models’ take hold, it will be essential to ensure patients, working closely with providers, have a strong voice.” Click here to view the blog post.
2. PCORI Selects 30 Individuals, Small Groups for First "Pipeline to Proposal" Awards
According to a recent press release, “The Patient-Centered Outcomes Research Institute (PCORI) has approved 30 projects under the pilot phase of its new ‘Pipeline to Proposal’ awards program. These Tier I awards, totaling $432,100 in requested funding, are the first to be made through this initiative, which provides seed money to encourage development of partnerships and health research project ideas among individuals and groups who want to take an active role in research but may not have opportunities to do so... The 30 projects were selected by review panels made up of patients, stakeholders, and researchers. The proposed projects are approved subject to a programmatic and budget review by PCORI staff and the negotiation of a formal award contract.” Click here to view the press release.
3. PCORI Blog: Evaluating PCORI’s Progress and Promise: A New Year’s Review
PCORI’s Executive Director Joe Selby recently commented on The PCORI Blog, “We look forward with great excitement to our first opportunity to review the findings of the research we've funded. Results from the 50 PCORI Pilot Projects we approved in 2012 will start to become available toward year's end. Although not head-to-head comparative studies, these projects will inform the healthcare community on the most effective methods for engaging patients in research and care delivery. We expect these findings to bolster our case for giving patients and other stakeholders a prominent voice in research, as well as to suggest refinements to our engagement strategies.” Click here to view the blog post.
4. Pink Sheet: Drug-Related Topics Among PCORI Priorities For Large Pragmatic Clinical CER Trials
Gregory Twachtman of The Pink Sheet reports, “For the large scale trials, PCORI plans to fund six to nine projects with a total of $5 million to $15 million per project during each funding cycle, with studies lasting up to five years, though applicants will be encouraged to submit proposals that are shorter than the five-year duration. The request for applications will be a standing request and the institute expects to make two solicitations a year for this research beginning in the first quarter of 2014.” Click here to view the article (subscription required).
5. AAMC Blog: New PCORI Methodology Report Offers Guidelines, Expectations for Comparative Effectiveness Research
Sarah Mann of the Association of American Medical Colleges (AAMC) Reporter writes, “The Patient-Centered Outcomes Research Institute (PCORI) last month released its revised PCORI Methodology Report, which offers guidelines on minimal requirements and best practices for researchers conducting patient-centered outcomes research, also known as comparative effectiveness research (CER)… ‘The PCORI methods guidelines are a giant step toward achieving patient-centered care in the United States. They will encourage researchers to use the most appropriate scientific methods to inform the right care for the right person at the right time,’ said Scott Braithwaite, M.D., chief of the Division of Comparative Effectiveness and Decision Sciences at New York University School of Medicine.” Click here to view the article.
6. MedPage Today: Blog: Evidence-Based Medicine and the Limitations of Research
In a blog post on MedPage Today’s KevinMD.com, Dr. Elana Miller comments, “Instead of practicing ‘evidence-based medicine’ as if the evidence were dogma, let's use research to move the practice of medicine forward while also remembering its limitations, including biases against publishing negative results and the agendas of the people doing or reporting the literature. Let's consider practicing ‘evidence-informed medicine’ instead, where we consider factors like safety, tolerability, and cost when deciding how much evidence we need to see before recommending a treatment.” Click here to view the blog post.