In this week's edition...
— PIPC Responds to CMS' GLOBE and GUARD Models, Also Known as 'Most Favored Nation.' Click here to read PIPC's full statement.
— RealClear Discusses 'Most Favored Nation,' Criticizing the Policy's Impact on Patient Access. Click here to view the article.
— MFN May Also Cut Off Rural America. Click here to view the article.
— The Well News (Opinion): Most Favored Nation Drug Pricing Fails Patients and their Caregivers. View the opinion here.
— PIPC Data Mine Blog: Why Patients Shouldn’t Bear Individual Harms for Better Population Averages. View the new PIPC Data Mine Blog here.
— PIPC Chairman Coelho Testifies to Oregon Department of Consumer and Business Services. View Chairman Coelho’s testimony here. View the testimony from Disability Rights Oregon here. Learn more about the hearing here.
— White House Issues RFI on Scientific Research & AI. See details below.
— Prasad and Makary Discuss Novel FDA Plausible Mechanism Pathway. Click here to read the NEJM publication.
— Reps. Cammack and Hern Introduce QALY Ban Bill. See details below.
— Opportunity: Sign an Open Letter Rejecting Use of QALYs and Similar Measures. See details below.
— Update on the Texas v. Kennedy Lawsuit. See details below.
— Emerging Threats in States for Use of Discriminatory Metrics. See details below.
— What Happens in Countries Using QALYs and Cost-Based Thresholds? See details below.
— ICER's QALY-Based Study Topics. See details below.
— Upcoming Events and Webinars. See details below.
— PIPC Responds to CMS' GLOBE and GUARD Models, Also Known as 'Most Favored Nation.' Click here to read PIPC's full statement.
— RealClear Discusses 'Most Favored Nation,' Criticizing the Policy's Impact on Patient Access. Click here to view the article.
— MFN May Also Cut Off Rural America. Click here to view the article.
— The Well News (Opinion): Most Favored Nation Drug Pricing Fails Patients and their Caregivers. View the opinion here.
— PIPC Data Mine Blog: Why Patients Shouldn’t Bear Individual Harms for Better Population Averages. View the new PIPC Data Mine Blog here.
— PIPC Chairman Coelho Testifies to Oregon Department of Consumer and Business Services. View Chairman Coelho’s testimony here. View the testimony from Disability Rights Oregon here. Learn more about the hearing here.
— White House Issues RFI on Scientific Research & AI. See details below.
— Prasad and Makary Discuss Novel FDA Plausible Mechanism Pathway. Click here to read the NEJM publication.
— Reps. Cammack and Hern Introduce QALY Ban Bill. See details below.
— Opportunity: Sign an Open Letter Rejecting Use of QALYs and Similar Measures. See details below.
— Update on the Texas v. Kennedy Lawsuit. See details below.
— Emerging Threats in States for Use of Discriminatory Metrics. See details below.
— What Happens in Countries Using QALYs and Cost-Based Thresholds? See details below.
— ICER's QALY-Based Study Topics. See details below.
— Upcoming Events and Webinars. See details below.
What We're Reading
PIPC welcomes new members to advance our efforts to assure patients and people with disabilities are at the center of research and policy! Please reach out to [email protected] for more information.
1. PIPC Responds to CMS' GLOBE and GUARD Models, Also Known as 'Most Favored Nation.' On December 19, the Trump Administration announced the Global Benchmark for Efficient Drug Pricing (GLOBE) and Guarding U.S. Medicare Against Rising Drug Costs (GUARD) Models. While PIPC appreciates the administration’s goals to lower health costs for patients, it remains concerned that the latest proposals to advance a Most Favored Nation pricing model for drugs will, in effect, import the worst of foreign health systems – their reliance on discriminatory value assessments. Stories from outside the U.S., like that of Alice’s family, illustrate why quality-adjusted life years (QALYs) have no place in U.S. policy. Patients do not have the luxury of time.
Click here to read PIPC's full statement.
2. RealClear Discusses 'Most Favored Nation,' Criticizing the Policy's Impact on Patient Access. RealClear recently released an article denouncing the Trump administration's 'most favored nation' (MFN) policy through a discussion about its unintentional worsening of access to care for patients. The article explains the following: "Underlying the current MFN debate lies the assumption that other countries value the 'latest and greatest' treatments the same way we do, and those countries would pay more if prompted. Unfortunately, that's not the case. Foreign health systems that rely on price controls frequently ration care, delay access to new treatments, or deny coverage altogether."
Click here to view the article.
3. MFN May Also Cut Off Rural America. Dr. N. Adam Brown, a practicing emergency physician, entrepreneur, and healthcare executive, penned an opinion in Medpage raising concerns about the impact of a Most Favored Nation policy on rural America. He stated, "Now dial in MFN. It is not that, amid price compression, a company will sit in a boardroom and say, 'Let's cut off rural patients.' But every thin margin in the distribution chain will get thinner. Wholesalers will negotiate harder. Pharmacies will drop low-volume products. Assistance programs that do not directly show up in a stock price get trimmed. When an infusion suite decides which therapies to carry, the high-complexity drug used by a small panel of rural patients will not be at the top of the list.”
Click here to view the article.
4. The Well News (Opinion): Most Favored Nation Drug Pricing Fails Patients and their Caregivers. Marvell Adams Jr., CEO, Caregiver Action Network, penned an opinion piece stating, "Supporters bill MFN as a way to cut costs. In reality, it would import Europe’s system of government-set prices, and with it the predictable consequences: fewer available treatments, longer waits and stalled medical innovation. Patient care would suffer, and caregivers would be left to shoulder even more.” The opinion clarifies that, in Europe, patients often wait more than a year for new therapies that patients in the United States can get within months or even weeks.
View the opinion here.
5. PIPC Data Mine Blog: Why Patients Shouldn’t Bear Individual Harms for Better Population Averages. The recent draft Health Technology Assessment (HTA) methods report released by the Health Economics Methods Advisory (HEMA) group makes it crystal clear – policy grounded in convention HTA methods (like the QALY) are willing to harm the individual for the sake of the formula-derived average. The report was produced by a collaboration led by the Institute for Clinical and Economic Review (ICER) and health agencies in the UK and Canada. It underscores PIPC’s position on why policymakers must reject government policy based on national HTA, whether through direct use of ICER-style cost-effectiveness thresholds or indirect reliance on HTA-based decisions made in other countries.
View the new PIPC Data Mine Blog here.
6. PIPC Chairman Coelho Testifies to Oregon Department of Consumer and Business Services. PIPC Chairman Tony Coelho provided testimony at an Oregon hearing on drug prices, telling his own personal story as well as underscoring the inconsistency of Oregon’s law barring the use of QALYs and similar measures with the presence of the Institute for Clinical and Economic Review (ICER) which views QALYs as the “gold standard” for value assessment. Additionally, Disability Rights Oregon and other groups representing people with disabilities provided comments expressing concern that ICER was invited to participate. The letter stated, "it is highly inappropriate for ICER to be considered an advisor to the state of Oregon in makers related to our health system. State and federal policy have made it clear that QALYs and similar measures have no place here because we are a state that values people with disabilities and serious chronic conditions. Therefore, we urge reconsideration of ICER’s presence at this public hearing and in future discussions convened by the Department and Consumer Business Services (DCBS).”
View Chairman Coelho’s testimony here. View the testimony from Disability Rights Oregon here. Learn more about the hearing here.
7. White House Issues RFI on Scientific Research & AI. On November 24, President Trump signed an executive order (EO) to promote the growth and development artificial intelligence (AI) within the nation. In alignment with a previous administrative initiative, America's AI Action Plan, the announcement establishes "Mission Genesis," a national effort to propel AI innovation through the collection of U.S. resources and research. Built within a newly created infrastructure, the American Science and Security Platform, the EO seeks instill a sense of urgency in national AI development.
Of note, the White House Office of Science and Technology Policy (OSTP) released a request for information (RFI) pertaining to the recent EO. According to the notice, "... OSTP seeks input from academia; private sector organizations; industry groups; state, local, and tribal governments; and other stakeholders regarding priorities for strengthening the science and technology ecosystem to support both the expansion of scientific knowledge and the mechanisms to transition these discoveries into the marketplace." OSTP is looking for answers to various questions detailed in its notice, including: (1) The RFI specifies various questions it seeks information for including "What specific Federal statutes, regulations, or policies create unnecessary barriers to scientific research or the deployment of research outcomes? Please describe the barrier, its impact on scientific progress, and potential remedies that would preserve legitimate policy objectives while enabling innovation." and (2) "What policy mechanisms would ensure that the benefits of federally-funded research—including access to resulting technologies, economic opportunities, and improved quality of life—reach all Americans?"
Click here to read the EO. Click here to learn more about the RIF. Click here to submit comments.
8. Prasad and Makary Discuss Novel FDA Plausible Mechanism Pathway. On November 12, Food and Drug Administration (FDA) Commissioner Marty Makary and Chief Medical and Scientific Officer Vinay Prasad published an essay in The New England Journal of Medicine (NEJM) discussing the FDA new “plausible mechanism pathway.” The new pathway intends to lay out an opportunity for therapies to gain approval when a randomized controlled trial is not feasible. This could be a helpful tool to get rare disease treatments to market if FDA is serious about its application.
Click here to read the NEJM publication.
9. Reps. Cammack and Hern Introduce QALY Ban Bill. Representatives Kat Cammack (FL-03) and Kevin Hern (OK-01) introduced the Protecting Health Care for All Patients Act to ensure that Americans with disabilities, chronic illnesses, and rare conditions are not devalued in federal health care decisions. This legislation prohibits the use of Quality-Adjusted Life Years (QALYs)—a metric that assigns lower value to lives with disabilities— and similar measures in federal programs like Medicare, Medicaid, CHIP, and ACA exchanges. “The use of so-called cost-effective measures like QALYs threatens access to lifesaving care for the most vulnerable Americans,” said Congresswoman Cammack. “I am honored to lead this legislation alongside my colleague Rep. Kevin Hern to ensure that no patient is denied treatment simply because a mathematical formula decided their life is worth less. Every American—regardless of disability, chronic illness, or rare condition—deserves equal access to care.”
View the press release here. View more information about the bill here. View PIPC's one pager here.
10. Opportunity: Sign an Open Letter Rejecting Use of QALYs and Similar Measures. In 2021, the Partnership to Improve Patient Care (PIPC), the American Association of People with Disabilities, and several organizations from the patient and disability communities partnered to publish an Open Letter that grounded our advocacy against policies that would reference QALYs and similar measures that devalue people with disabilities and older adults. Please join PIPC, ALS Association, Alliance for Aging Research, American Association of People with Disabilities, Epilepsy Foundation of America and Patients Rights Action Fund in signing a revised Open Letter! The threat for incorporating QALYs and similar measures into the American health system has grown with the last administration’s reference to QALY-based studies in the Medicare Drug Negotiation Program and in this administration's Executive Order seeking to model foreign countries that base drug prices on discriminatory value assessments. It is our goal to capitalize on the long history of robust, bipartisan opposition to QALY-based policies in Medicare and Medicaid that underscores America’s core belief that the lives of individuals with disabilities, older adults and infants are worth just as much as any other person.
The central theme of the updated letter is this: All lives are valuable, and our health care policy should adhere to this fundamental American belief. We strongly urge policymakers to reject policies that would devalue and ration care for any American whether modeled after foreign or domestic value assessment methodologies.
Click HERE to sign the updated Open Letter. Note we will add new signatories every few days to the updated letter which is available to share with policymakers here.
Click here to contact your Member of Congress.
11. Update on the Texas v. Kennedy Lawsuit. Texas v. Kennedy is a lawsuit brought by 17 states in federal court in the Northern District of Texas. The lawsuit challenges 2024 regulations from the U.S. Department of Health and Human Services (HHS), claiming that Section 504 of the Rehabilitation Act is unconstitutional.
As outlined by Bazelon, DREDF, The Arc, CPR and National Health Law Program, the Texas v. Kennedy case remains a significant threat to the rights of people with disabilities. The 17 states continue to challenge the updated Section 504 regulations, which include a ban on disability discrimination in medical treatment decisions including the use of discriminatory value assessments. On July 29, a Joint Status Report was filed by HHS and 17 states, requesting that the court continue the pause in the case. On October 27, another Joint Status Report was filed by the parties, requesting that the court continue the "stay" in the case. The parties have noted that they will file a new report on January 9, 2026.
Click here and scroll down to reach out to your State Attorney General.
Learn More About Emerging Threats in States for Use of Discriminatory Metrics
Several states are advancing policies that would reference quality-adjusted life years (QALYs) and similar measures known to discriminate and devalue people with disabilities and serious chronic conditions, despite laws barring their use. Contrary to the law, these measures are considered by some to be the “gold standard” for measuring cost effectiveness of treatments, including the Institute for Clinical and Economic Review (ICER) and by foreign countries. Their use as a reference for U.S. coverage and reimbursement decisions is concerning due to implications for access to care, as seen internationally where a focus on cost effectiveness disadvantages coverage of health care for people with conditions that are chronic or disabling. To keep track of state-based threats, several resources are available:
International News: What Happens in Countries Using QALYs and Cost-Based Thresholds?
Other countries are often referenced as examples of how the use of QALYs or similar cost-based thresholds impact access to care.
ICER's QALY-Based Study Topics
The Institute for Clinical Economic Review (ICER) conducts cost effectiveness studies for insurers using the cost-per-QALY methodology. ICER provides guidance on its website for patients and patient advocates to provide direct input related to their experiences with the disease. Click here to provide patient input. Click here to view the topics and deadlines.
View PIPC value assessment resources on gene therapies here, on health equity here and an analysis on lack of patient-centered outcomes in value assessment here.
Upcoming Events and Webinars
Colorado PDAB Meeting
January 9, 2026
Click here to view.
Minnesota PDAB Meeting
January 13, 2026
Click here to view.
Oregon PDAB Meeting
January 21, 2026
Click here to view.
Washington State PDAB Meeting
March 18, 2026
Click here to view.
PIPC welcomes new members to advance our efforts to assure patients and people with disabilities are at the center of research and policy! Please reach out to [email protected] for more information.
1. PIPC Responds to CMS' GLOBE and GUARD Models, Also Known as 'Most Favored Nation.' On December 19, the Trump Administration announced the Global Benchmark for Efficient Drug Pricing (GLOBE) and Guarding U.S. Medicare Against Rising Drug Costs (GUARD) Models. While PIPC appreciates the administration’s goals to lower health costs for patients, it remains concerned that the latest proposals to advance a Most Favored Nation pricing model for drugs will, in effect, import the worst of foreign health systems – their reliance on discriminatory value assessments. Stories from outside the U.S., like that of Alice’s family, illustrate why quality-adjusted life years (QALYs) have no place in U.S. policy. Patients do not have the luxury of time.
Click here to read PIPC's full statement.
2. RealClear Discusses 'Most Favored Nation,' Criticizing the Policy's Impact on Patient Access. RealClear recently released an article denouncing the Trump administration's 'most favored nation' (MFN) policy through a discussion about its unintentional worsening of access to care for patients. The article explains the following: "Underlying the current MFN debate lies the assumption that other countries value the 'latest and greatest' treatments the same way we do, and those countries would pay more if prompted. Unfortunately, that's not the case. Foreign health systems that rely on price controls frequently ration care, delay access to new treatments, or deny coverage altogether."
Click here to view the article.
3. MFN May Also Cut Off Rural America. Dr. N. Adam Brown, a practicing emergency physician, entrepreneur, and healthcare executive, penned an opinion in Medpage raising concerns about the impact of a Most Favored Nation policy on rural America. He stated, "Now dial in MFN. It is not that, amid price compression, a company will sit in a boardroom and say, 'Let's cut off rural patients.' But every thin margin in the distribution chain will get thinner. Wholesalers will negotiate harder. Pharmacies will drop low-volume products. Assistance programs that do not directly show up in a stock price get trimmed. When an infusion suite decides which therapies to carry, the high-complexity drug used by a small panel of rural patients will not be at the top of the list.”
Click here to view the article.
4. The Well News (Opinion): Most Favored Nation Drug Pricing Fails Patients and their Caregivers. Marvell Adams Jr., CEO, Caregiver Action Network, penned an opinion piece stating, "Supporters bill MFN as a way to cut costs. In reality, it would import Europe’s system of government-set prices, and with it the predictable consequences: fewer available treatments, longer waits and stalled medical innovation. Patient care would suffer, and caregivers would be left to shoulder even more.” The opinion clarifies that, in Europe, patients often wait more than a year for new therapies that patients in the United States can get within months or even weeks.
View the opinion here.
5. PIPC Data Mine Blog: Why Patients Shouldn’t Bear Individual Harms for Better Population Averages. The recent draft Health Technology Assessment (HTA) methods report released by the Health Economics Methods Advisory (HEMA) group makes it crystal clear – policy grounded in convention HTA methods (like the QALY) are willing to harm the individual for the sake of the formula-derived average. The report was produced by a collaboration led by the Institute for Clinical and Economic Review (ICER) and health agencies in the UK and Canada. It underscores PIPC’s position on why policymakers must reject government policy based on national HTA, whether through direct use of ICER-style cost-effectiveness thresholds or indirect reliance on HTA-based decisions made in other countries.
View the new PIPC Data Mine Blog here.
6. PIPC Chairman Coelho Testifies to Oregon Department of Consumer and Business Services. PIPC Chairman Tony Coelho provided testimony at an Oregon hearing on drug prices, telling his own personal story as well as underscoring the inconsistency of Oregon’s law barring the use of QALYs and similar measures with the presence of the Institute for Clinical and Economic Review (ICER) which views QALYs as the “gold standard” for value assessment. Additionally, Disability Rights Oregon and other groups representing people with disabilities provided comments expressing concern that ICER was invited to participate. The letter stated, "it is highly inappropriate for ICER to be considered an advisor to the state of Oregon in makers related to our health system. State and federal policy have made it clear that QALYs and similar measures have no place here because we are a state that values people with disabilities and serious chronic conditions. Therefore, we urge reconsideration of ICER’s presence at this public hearing and in future discussions convened by the Department and Consumer Business Services (DCBS).”
View Chairman Coelho’s testimony here. View the testimony from Disability Rights Oregon here. Learn more about the hearing here.
7. White House Issues RFI on Scientific Research & AI. On November 24, President Trump signed an executive order (EO) to promote the growth and development artificial intelligence (AI) within the nation. In alignment with a previous administrative initiative, America's AI Action Plan, the announcement establishes "Mission Genesis," a national effort to propel AI innovation through the collection of U.S. resources and research. Built within a newly created infrastructure, the American Science and Security Platform, the EO seeks instill a sense of urgency in national AI development.
Of note, the White House Office of Science and Technology Policy (OSTP) released a request for information (RFI) pertaining to the recent EO. According to the notice, "... OSTP seeks input from academia; private sector organizations; industry groups; state, local, and tribal governments; and other stakeholders regarding priorities for strengthening the science and technology ecosystem to support both the expansion of scientific knowledge and the mechanisms to transition these discoveries into the marketplace." OSTP is looking for answers to various questions detailed in its notice, including: (1) The RFI specifies various questions it seeks information for including "What specific Federal statutes, regulations, or policies create unnecessary barriers to scientific research or the deployment of research outcomes? Please describe the barrier, its impact on scientific progress, and potential remedies that would preserve legitimate policy objectives while enabling innovation." and (2) "What policy mechanisms would ensure that the benefits of federally-funded research—including access to resulting technologies, economic opportunities, and improved quality of life—reach all Americans?"
Click here to read the EO. Click here to learn more about the RIF. Click here to submit comments.
8. Prasad and Makary Discuss Novel FDA Plausible Mechanism Pathway. On November 12, Food and Drug Administration (FDA) Commissioner Marty Makary and Chief Medical and Scientific Officer Vinay Prasad published an essay in The New England Journal of Medicine (NEJM) discussing the FDA new “plausible mechanism pathway.” The new pathway intends to lay out an opportunity for therapies to gain approval when a randomized controlled trial is not feasible. This could be a helpful tool to get rare disease treatments to market if FDA is serious about its application.
Click here to read the NEJM publication.
9. Reps. Cammack and Hern Introduce QALY Ban Bill. Representatives Kat Cammack (FL-03) and Kevin Hern (OK-01) introduced the Protecting Health Care for All Patients Act to ensure that Americans with disabilities, chronic illnesses, and rare conditions are not devalued in federal health care decisions. This legislation prohibits the use of Quality-Adjusted Life Years (QALYs)—a metric that assigns lower value to lives with disabilities— and similar measures in federal programs like Medicare, Medicaid, CHIP, and ACA exchanges. “The use of so-called cost-effective measures like QALYs threatens access to lifesaving care for the most vulnerable Americans,” said Congresswoman Cammack. “I am honored to lead this legislation alongside my colleague Rep. Kevin Hern to ensure that no patient is denied treatment simply because a mathematical formula decided their life is worth less. Every American—regardless of disability, chronic illness, or rare condition—deserves equal access to care.”
View the press release here. View more information about the bill here. View PIPC's one pager here.
10. Opportunity: Sign an Open Letter Rejecting Use of QALYs and Similar Measures. In 2021, the Partnership to Improve Patient Care (PIPC), the American Association of People with Disabilities, and several organizations from the patient and disability communities partnered to publish an Open Letter that grounded our advocacy against policies that would reference QALYs and similar measures that devalue people with disabilities and older adults. Please join PIPC, ALS Association, Alliance for Aging Research, American Association of People with Disabilities, Epilepsy Foundation of America and Patients Rights Action Fund in signing a revised Open Letter! The threat for incorporating QALYs and similar measures into the American health system has grown with the last administration’s reference to QALY-based studies in the Medicare Drug Negotiation Program and in this administration's Executive Order seeking to model foreign countries that base drug prices on discriminatory value assessments. It is our goal to capitalize on the long history of robust, bipartisan opposition to QALY-based policies in Medicare and Medicaid that underscores America’s core belief that the lives of individuals with disabilities, older adults and infants are worth just as much as any other person.
The central theme of the updated letter is this: All lives are valuable, and our health care policy should adhere to this fundamental American belief. We strongly urge policymakers to reject policies that would devalue and ration care for any American whether modeled after foreign or domestic value assessment methodologies.
Click HERE to sign the updated Open Letter. Note we will add new signatories every few days to the updated letter which is available to share with policymakers here.
Click here to contact your Member of Congress.
11. Update on the Texas v. Kennedy Lawsuit. Texas v. Kennedy is a lawsuit brought by 17 states in federal court in the Northern District of Texas. The lawsuit challenges 2024 regulations from the U.S. Department of Health and Human Services (HHS), claiming that Section 504 of the Rehabilitation Act is unconstitutional.
As outlined by Bazelon, DREDF, The Arc, CPR and National Health Law Program, the Texas v. Kennedy case remains a significant threat to the rights of people with disabilities. The 17 states continue to challenge the updated Section 504 regulations, which include a ban on disability discrimination in medical treatment decisions including the use of discriminatory value assessments. On July 29, a Joint Status Report was filed by HHS and 17 states, requesting that the court continue the pause in the case. On October 27, another Joint Status Report was filed by the parties, requesting that the court continue the "stay" in the case. The parties have noted that they will file a new report on January 9, 2026.
Click here and scroll down to reach out to your State Attorney General.
Learn More About Emerging Threats in States for Use of Discriminatory Metrics
Several states are advancing policies that would reference quality-adjusted life years (QALYs) and similar measures known to discriminate and devalue people with disabilities and serious chronic conditions, despite laws barring their use. Contrary to the law, these measures are considered by some to be the “gold standard” for measuring cost effectiveness of treatments, including the Institute for Clinical and Economic Review (ICER) and by foreign countries. Their use as a reference for U.S. coverage and reimbursement decisions is concerning due to implications for access to care, as seen internationally where a focus on cost effectiveness disadvantages coverage of health care for people with conditions that are chronic or disabling. To keep track of state-based threats, several resources are available:
- Patient Access Project State-by-state tracker of QALY-based policies and legislation, including Prescription Drug Affordability Boards, P&T Committees, and reference to discriminatory policies in foreign countries.
- Value Of Care Coalition advocacy tracker of state PDAB comment opportunities.
- AIMED Alliance resources and tracker of state PDAB activities.
- PIPC resources on use of QALYs and similar measures internationally.
- EACH/PIC Coalition resources.
- Value Our Health toolkit and resources on implications for disability discrimination.
International News: What Happens in Countries Using QALYs and Cost-Based Thresholds?
Other countries are often referenced as examples of how the use of QALYs or similar cost-based thresholds impact access to care.
- Belgium. The Cystic Fibrosis Association (Association Muco) revealed that dozens of patients are still waiting for their treatments to be reimbursed because of prolonged drug price negotiations.
- Canada. A Type 1 diabetic who recently moved to Nova Scotia says they paid hundreds of dollars out of pocket while trying to apply for provincial programs that help cover the cost of insulin and supplies.
- Canada. Access to a vital therapy, known for treating adults with multiple myeloma, is being stalled in Canada.
- Canada. A family of a toddler with cerebral palsy has to travel abroad in order to seamlessly access treatment.
- Korea. The Ministry of Health and Welfare is honing in on drug pricing reforms centered around the use of discriminatory QALYs and ICER assessments.
- United Kingdom. A form of immunotherapy for lung cancer is not available for coverage under the NHS as patients continue to wait for a decision.
ICER's QALY-Based Study Topics
The Institute for Clinical Economic Review (ICER) conducts cost effectiveness studies for insurers using the cost-per-QALY methodology. ICER provides guidance on its website for patients and patient advocates to provide direct input related to their experiences with the disease. Click here to provide patient input. Click here to view the topics and deadlines.
View PIPC value assessment resources on gene therapies here, on health equity here and an analysis on lack of patient-centered outcomes in value assessment here.
- COVID-19: Research Protocol available. Public meeting: June 2026.
- Narcolepsy: Research Protocol available. Public meeting: May 2026.
- IgA Nephropathy: Draft Evidence Report available. Public comments due January 14, 2026. Public meeting: February 2026.
- Launch Price and Access Report: Drug Approvals from 2023-2024: Final Report and Webinar Recording available.
- Smoking Cessation: Evidence Report available. Public meeting: January 2026.
- Obesity Management: Final Evidence Report and Meeting Summary available.
- Examining Strategies to Ensure Affordable Access for Obesity Medications: White Paper published on April 9, 2025.
- Non-Cystic Fibrosis Bronchiectasis: Final Evidence Report and Meeting Summary available.
- Spinal Muscular Atrophy: Final Evidence Report and Meeting Summary available.
- Multiple Sclerosis — SPMS: Final Evidence Report and Meeting Summary available.
- Retinitis Pigmentosa: Final Evidence Report and Meeting Summary available.
Upcoming Events and Webinars
Colorado PDAB Meeting
January 9, 2026
Click here to view.
Minnesota PDAB Meeting
January 13, 2026
Click here to view.
Oregon PDAB Meeting
January 21, 2026
Click here to view.
Washington State PDAB Meeting
March 18, 2026
Click here to view.
