In This Week’s Issue:
1. PIPC Chairman Coelho Outlines Concerns with ISPOR’s Value Assessment Frameworks Initiative, click here to read the letter.
2. Vox: Trump wants to cut health research. This Republican won’t let him, click here to read the article.
3. Health Affairs: Measuring Value Based On What Matters To Patients: A New Value Assessment Framework, click here to read the blog.
4. AMJC Video: Tailored Approach to Value Assessment Is Necessary, click here to watch the video.
5. PharmTech: Value-Based Pricing Viewed as Most Potentially Transformative Factor Facing the Industry, click here to read the article.
6. Clinical Leader: Patient Centricity In Clinical Trials: Lessons Learned From Big Pharma, click here to read the article.
7. Article: Patient-Centered Digital Education Improves Adherence Rates, Survival for Patients with Lung Cancer, click here to read the article.
8. Epilepsy Foundation: 2017-2018 AAHD Frederick J. Krause Scholarship on Health and Disability Click here to apply.
9. Upcoming Events and Webinars, see details below
10. Medical Journal Articles, see details below.
11. AHRQ Effective Program Updates, see details below.
1. PIPC Chairman Coelho Outlines Concerns with ISPOR’s Value Assessment Frameworks Initiative, click here to read the letter.
2. Vox: Trump wants to cut health research. This Republican won’t let him, click here to read the article.
3. Health Affairs: Measuring Value Based On What Matters To Patients: A New Value Assessment Framework, click here to read the blog.
4. AMJC Video: Tailored Approach to Value Assessment Is Necessary, click here to watch the video.
5. PharmTech: Value-Based Pricing Viewed as Most Potentially Transformative Factor Facing the Industry, click here to read the article.
6. Clinical Leader: Patient Centricity In Clinical Trials: Lessons Learned From Big Pharma, click here to read the article.
7. Article: Patient-Centered Digital Education Improves Adherence Rates, Survival for Patients with Lung Cancer, click here to read the article.
8. Epilepsy Foundation: 2017-2018 AAHD Frederick J. Krause Scholarship on Health and Disability Click here to apply.
9. Upcoming Events and Webinars, see details below
10. Medical Journal Articles, see details below.
11. AHRQ Effective Program Updates, see details below.
1. PIPC Chairman Coelho Outlines Concerns with ISPOR’s Value Assessment Frameworks Initiative
Last Friday, Partnership to Improve Patient Care (PIPC) Chairman Tony Coelho submitted a letter to the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Chief Science Officer Richard Wilke outlining “strong” concerns about the recent draft of a U.S. Value Assessment Frameworks initiative led by ISPOR. In the letter, Chairman Coelho expresses disappointment with ISPOR’s recommendations, noting that they “do not reflect advancement as indicated to be ISPOR’s mission.” “We understand the challenge of assessing value in health care in a manner that is centered on the characteristics, needs and preferences of the individual patient versus defining value based on what is cost effective for an ‘average’ patient, and appreciate that the work that the ISPOR Special Task Force on Value Assessment has undertaken is difficult,” wrote Chairman Coelho. “That said, we have significant concerns regarding the recommendations that ISPOR outlines in its draft report…PIPC was hopeful that the Special Task Force was an opportunity to further advance novel, patient- centered methods for assessing treatment value. We are disappointed that ISPOR instead doubled down on the use of the cost-per-QALY metric in direct contradiction to the patient-centeredness movement.”
Chairman Coelho also states: “PIPC urges ISPOR to develop and implement a process for patient engagement that reflects the best practices modeled by organizations like PCORI, FDA, and others described above. With a meaningful patient engagement infrastructure in place moving forward, PIPC is excited to continue to be an engaged stakeholder in the U.S. Value Assessment Frameworks Initiative.” Click here to read the letter.
2. Vox: Trump wants to cut health research. This Republican won’t let him.
Julia Belluz sits down for an interview in Vox with Rep. Tom Cole (R-OK), who offers his thoughts on President Trump’s cuts to the National Institutes of Health. “Some attribute Cole’s support for research to his family’s health issues. He watched his father succumb to Alzheimer’s disease. His wife, Ellen, has battled multiple sclerosis for more than two decades. But Cole insists it’s not just the personal that drives his policymaking — it’s simply that funding medical science is a no-brainer, good for Americans individually as well as for the economy. I reached out to Cole to try to and understand why Republicans support health science while denying other kinds of science and how medical research became a bipartisan issue. We also discussed why Trump is much more likely to have to deal with a pandemic than an act of terrorism, and how he’ll respond to the latest budget.” Click here to read the article.
3. Health Affairs: Measuring Value Based On What Matters To Patients: A New Value Assessment Framework
A new piece in the Health Affairs Blog touches on the importance of the patient perspective on value frameworks.“...The need to incorporate the patient perspective on value has been a key talking point for all types of stakeholders in critiquing value assessment models. It is first on the [National Pharmaceutical Council’s] list of ‘improvements,’ and the NPC is far from alone in this perspective. Some framework developers have explicitly articulated different purposes for their frameworks, such as driving payer and policy maker decision making.” Click here to read the blog.
4. AMJC Video: Tailored Approach to Value Assessment Is Necessary
The American Journal of Managed Care released a new video featuring Dr. Irene Hollin, who notes that a tailored approach to value assessment will help drive innovation and impact patient outcomes and access to care. “It’s not possible to have a one-size-fits-all approach to value assessment in the US healthcare system. We need a tailored approach, and to do so, this means that we need to understand, define, and measure value accurately, and then tailor our approach to the stakeholder, to the health condition, and to the subpopulation. This is imperative because there are substantial repercussions for reimbursement, patient access, and patient outcomes. It’s also important that we have a tailored approach because this is what will help drive innovation and make sure that future therapies are developed with what the patients want in mind.” Click here to watch the video.
5. PharmTech: Value-Based Pricing Viewed as Most Potentially Transformative Factor Facing the Industry
A new article in Pharmaceutical Technology touches on the discussion and debate surrounding value-based medicine “...In its Global Healthcare Leaders survey for 2017, Lazard asked more than 200 C-level executives and more than 100 investors in the pharmaceutical industry, medical devices and healthcare services what the most important issues, opportunities and challenges were...[R]espondents cited the move to value-based medicine and risk-based pricing models as the most significant change facing the industry, suggesting that it might even have more of an impact than scientific breakthroughs. The new value-based environment will require increased innovation and new business models, respondents said.” Click here to read the article.
6. Clinical Leader: Patient Centricity In Clinical Trials: Lessons Learned From Big Pharma
Clinical Leader discusses the trends in clinical trials that focus on a more patient-centered approach. “...[W]hat does it mean to be patient centric, practically speaking? What tactics are leading pharma companies employing to make centricity a reality in their trials? To find out, Clinical Leader reached out to patient centricity experts at four Big Pharma companies...[T]hese leaders describe their recent patient centricity initiatives, the technologies they've employed, and the specific benefits their efforts have yielded for their companies and their patients.” Click here to read the article.
7. Article: Patient-Centered Digital Education Improves Adherence Rates, Survival for Patients with Lung Cancer
Zachary Bessette reports in the Journal of Clinical Pathways on a patient-centered digital education initiative that is having a positive impact on lung cancer patients. “Patients with lung cancer who received and viewed a digital series of education about their intravenous treatment were more likely to remain adherent and improve their survival rates, according to research that will be presented at the 2017 ASCO Annual Meeting...” Click here to read the article.
8. Epilepsy Foundation: 2017-2018 AAHD Frederick J. Krause Scholarship on Health and Disability
The American Association on Health and Disability’s Frederick J. Krause Scholarship on Health and Disability is currently accepting applications. The scholarship honors Frederick J. Krause, a lifelong advocate for those with disabilities who passed away in 2014. Beginning with his role as a special education teacher, Mr. Krause’s distinguished career in advocacy included service in the federal government and the cofounding of the American Association on Health and Disability. The scholarship pays tribute to Mr. Krause by awarding scholarships to students with disabilities that are pursuing an education on disability-related topics. Click here to apply.
9. Upcoming Events and Webinars
ICER: Orphan Drug Assessment and Pricing Summit
May 31, 2017
Click here for details.
Webinar: Observational Research: Gathering Evidence in the 21st Century
June 1, 2017
Click here for details.
Examples from the Field (TENTATIVE Outreach Series)
June 7, 2017
Click here for details.
PCORnet Best Practice Sharing Session – Leveraging Social Media to Raise Awareness and Build Community
June 8, 2017
Click here for details.
Key Evidence Gaps in Insomnia Research: Can CER Help Answer Questions About Chronic Insomnia? A PCORI Stakeholder Workshop
June 13, 2017
Click here for details.
PCORI Board of Governors Meeting
June 20, 2017
Click here for details.
PCORI at AcademyHealth's Annual Research Meeting 2017
June 25-27, 2017
Click here for details.
Eugene Washington PCORI Engagement Awards: Key Information and Updates
June 27, 2017
Click here for details.
Introduction to HEOR: Principles and Practice in Health Care Decision Making
October 5-8
Click here for details.
2017 PCORI Annual Meeting
October 31-November 2
Click here for details.
10. Medical Journal Articles
Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial, click here to view.
Why Patients Should Be Involved in Health Technology Assessment, click here to view.
Health Care Professionals' Attitudes Towards Evidence-based Medicine in the Workers' Compensation Setting: A Cohort Study, click here to view
Why Value Framework Assessments Arrive at Different Conclusions: A Multiple Myeloma Case Study, click here to view.
Laboratory Formulary: A Model for High-Value Evidence-Based Medicine, click here to view.
Lower Risk of Heart Failure and Death in Patients Initiated on SGLT-2 Inhibitors Versus Other Glucose-Lowering Drugs: The CVD-REAL Study, click here to view.
Has Evidence-Based Medicine Ever Been Modern? A Latour-Inspired Understanding of a Changing EBM, click here to view.
‘Pragmatic' and ‘Explanatory' Attitudes to Randomized Trials, click here to view.
Methods and Impact of Engagement in Research, from Theory to Practice and Back Again: Early Findings from the Patient-Centered Outcomes Research Institute, click here to view.
Enhancing Comparative Effectiveness Research With Automated Pediatric Pneumonia Detection in a Multi-Institutional Clinical Repository: A PHIS+ Pilot Study, click here to view.
The Influence of Time Horizon on Results of Cost-Effectiveness Analyses, click here to view.
A Longitudinal Analysis of Data Quality in a Large Pediatric Data Research Network, click here to view.
Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial, click here to view.
May Issue: Journal of Comparative Effectiveness Research, click here to view.
A Real-World Approach to Evidence-Based Medicine in General Practice: A Competency Framework Derived from a Systematic Review and Delphi Process, click here to view.
Comparative Effectiveness of Prostate Cancer Treatments for Patient-Centered Outcomes: A Systematic Review and Meta-Analysis (PRISMA Compliant), click here to view.
11. AHRQ Effective Program Updates
Drug Therapy for Early Rheumatoid Arthritis in Adults – An Update -- Research Protocol, click here to view.
Psychological and Pharmacological Treatments for Adults with Posttraumatic Stress Disorder (PTSD): A Systematic Review Update -- Research Protocol, click here to view
Tympanostomy Tubes in Children with Otitis Media -- Final Report, click here to view
Treatment of Osteoarthritis of the Knee: An Update Review -- Final Report, click here to view.
Assessment Tools for Palliative Care -- Final Report, click here to view.
Noninvasive, Nonpharmacological Treatment for Chronic Pain, click here to view.
The Role of Immunotherapy in the Treatment of Asthma, click here to view
Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy -- Final Report, click here to view.
Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma, clickhere to view.
Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia -- Final Report, click here to view
First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update -- Final Report, click here to view.
Strategies for Improving the Lives of Women Aged 40 and Above Living With HIV/AIDS -- Disposition of Comments, click here to view.
Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review -- Research Protocol, click here to view.
Last Friday, Partnership to Improve Patient Care (PIPC) Chairman Tony Coelho submitted a letter to the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Chief Science Officer Richard Wilke outlining “strong” concerns about the recent draft of a U.S. Value Assessment Frameworks initiative led by ISPOR. In the letter, Chairman Coelho expresses disappointment with ISPOR’s recommendations, noting that they “do not reflect advancement as indicated to be ISPOR’s mission.” “We understand the challenge of assessing value in health care in a manner that is centered on the characteristics, needs and preferences of the individual patient versus defining value based on what is cost effective for an ‘average’ patient, and appreciate that the work that the ISPOR Special Task Force on Value Assessment has undertaken is difficult,” wrote Chairman Coelho. “That said, we have significant concerns regarding the recommendations that ISPOR outlines in its draft report…PIPC was hopeful that the Special Task Force was an opportunity to further advance novel, patient- centered methods for assessing treatment value. We are disappointed that ISPOR instead doubled down on the use of the cost-per-QALY metric in direct contradiction to the patient-centeredness movement.”
Chairman Coelho also states: “PIPC urges ISPOR to develop and implement a process for patient engagement that reflects the best practices modeled by organizations like PCORI, FDA, and others described above. With a meaningful patient engagement infrastructure in place moving forward, PIPC is excited to continue to be an engaged stakeholder in the U.S. Value Assessment Frameworks Initiative.” Click here to read the letter.
2. Vox: Trump wants to cut health research. This Republican won’t let him.
Julia Belluz sits down for an interview in Vox with Rep. Tom Cole (R-OK), who offers his thoughts on President Trump’s cuts to the National Institutes of Health. “Some attribute Cole’s support for research to his family’s health issues. He watched his father succumb to Alzheimer’s disease. His wife, Ellen, has battled multiple sclerosis for more than two decades. But Cole insists it’s not just the personal that drives his policymaking — it’s simply that funding medical science is a no-brainer, good for Americans individually as well as for the economy. I reached out to Cole to try to and understand why Republicans support health science while denying other kinds of science and how medical research became a bipartisan issue. We also discussed why Trump is much more likely to have to deal with a pandemic than an act of terrorism, and how he’ll respond to the latest budget.” Click here to read the article.
3. Health Affairs: Measuring Value Based On What Matters To Patients: A New Value Assessment Framework
A new piece in the Health Affairs Blog touches on the importance of the patient perspective on value frameworks.“...The need to incorporate the patient perspective on value has been a key talking point for all types of stakeholders in critiquing value assessment models. It is first on the [National Pharmaceutical Council’s] list of ‘improvements,’ and the NPC is far from alone in this perspective. Some framework developers have explicitly articulated different purposes for their frameworks, such as driving payer and policy maker decision making.” Click here to read the blog.
4. AMJC Video: Tailored Approach to Value Assessment Is Necessary
The American Journal of Managed Care released a new video featuring Dr. Irene Hollin, who notes that a tailored approach to value assessment will help drive innovation and impact patient outcomes and access to care. “It’s not possible to have a one-size-fits-all approach to value assessment in the US healthcare system. We need a tailored approach, and to do so, this means that we need to understand, define, and measure value accurately, and then tailor our approach to the stakeholder, to the health condition, and to the subpopulation. This is imperative because there are substantial repercussions for reimbursement, patient access, and patient outcomes. It’s also important that we have a tailored approach because this is what will help drive innovation and make sure that future therapies are developed with what the patients want in mind.” Click here to watch the video.
5. PharmTech: Value-Based Pricing Viewed as Most Potentially Transformative Factor Facing the Industry
A new article in Pharmaceutical Technology touches on the discussion and debate surrounding value-based medicine “...In its Global Healthcare Leaders survey for 2017, Lazard asked more than 200 C-level executives and more than 100 investors in the pharmaceutical industry, medical devices and healthcare services what the most important issues, opportunities and challenges were...[R]espondents cited the move to value-based medicine and risk-based pricing models as the most significant change facing the industry, suggesting that it might even have more of an impact than scientific breakthroughs. The new value-based environment will require increased innovation and new business models, respondents said.” Click here to read the article.
6. Clinical Leader: Patient Centricity In Clinical Trials: Lessons Learned From Big Pharma
Clinical Leader discusses the trends in clinical trials that focus on a more patient-centered approach. “...[W]hat does it mean to be patient centric, practically speaking? What tactics are leading pharma companies employing to make centricity a reality in their trials? To find out, Clinical Leader reached out to patient centricity experts at four Big Pharma companies...[T]hese leaders describe their recent patient centricity initiatives, the technologies they've employed, and the specific benefits their efforts have yielded for their companies and their patients.” Click here to read the article.
7. Article: Patient-Centered Digital Education Improves Adherence Rates, Survival for Patients with Lung Cancer
Zachary Bessette reports in the Journal of Clinical Pathways on a patient-centered digital education initiative that is having a positive impact on lung cancer patients. “Patients with lung cancer who received and viewed a digital series of education about their intravenous treatment were more likely to remain adherent and improve their survival rates, according to research that will be presented at the 2017 ASCO Annual Meeting...” Click here to read the article.
8. Epilepsy Foundation: 2017-2018 AAHD Frederick J. Krause Scholarship on Health and Disability
The American Association on Health and Disability’s Frederick J. Krause Scholarship on Health and Disability is currently accepting applications. The scholarship honors Frederick J. Krause, a lifelong advocate for those with disabilities who passed away in 2014. Beginning with his role as a special education teacher, Mr. Krause’s distinguished career in advocacy included service in the federal government and the cofounding of the American Association on Health and Disability. The scholarship pays tribute to Mr. Krause by awarding scholarships to students with disabilities that are pursuing an education on disability-related topics. Click here to apply.
9. Upcoming Events and Webinars
ICER: Orphan Drug Assessment and Pricing Summit
May 31, 2017
Click here for details.
Webinar: Observational Research: Gathering Evidence in the 21st Century
June 1, 2017
Click here for details.
Examples from the Field (TENTATIVE Outreach Series)
June 7, 2017
Click here for details.
PCORnet Best Practice Sharing Session – Leveraging Social Media to Raise Awareness and Build Community
June 8, 2017
Click here for details.
Key Evidence Gaps in Insomnia Research: Can CER Help Answer Questions About Chronic Insomnia? A PCORI Stakeholder Workshop
June 13, 2017
Click here for details.
PCORI Board of Governors Meeting
June 20, 2017
Click here for details.
PCORI at AcademyHealth's Annual Research Meeting 2017
June 25-27, 2017
Click here for details.
Eugene Washington PCORI Engagement Awards: Key Information and Updates
June 27, 2017
Click here for details.
Introduction to HEOR: Principles and Practice in Health Care Decision Making
October 5-8
Click here for details.
2017 PCORI Annual Meeting
October 31-November 2
Click here for details.
10. Medical Journal Articles
Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial, click here to view.
Why Patients Should Be Involved in Health Technology Assessment, click here to view.
Health Care Professionals' Attitudes Towards Evidence-based Medicine in the Workers' Compensation Setting: A Cohort Study, click here to view
Why Value Framework Assessments Arrive at Different Conclusions: A Multiple Myeloma Case Study, click here to view.
Laboratory Formulary: A Model for High-Value Evidence-Based Medicine, click here to view.
Lower Risk of Heart Failure and Death in Patients Initiated on SGLT-2 Inhibitors Versus Other Glucose-Lowering Drugs: The CVD-REAL Study, click here to view.
Has Evidence-Based Medicine Ever Been Modern? A Latour-Inspired Understanding of a Changing EBM, click here to view.
‘Pragmatic' and ‘Explanatory' Attitudes to Randomized Trials, click here to view.
Methods and Impact of Engagement in Research, from Theory to Practice and Back Again: Early Findings from the Patient-Centered Outcomes Research Institute, click here to view.
Enhancing Comparative Effectiveness Research With Automated Pediatric Pneumonia Detection in a Multi-Institutional Clinical Repository: A PHIS+ Pilot Study, click here to view.
The Influence of Time Horizon on Results of Cost-Effectiveness Analyses, click here to view.
A Longitudinal Analysis of Data Quality in a Large Pediatric Data Research Network, click here to view.
Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial, click here to view.
May Issue: Journal of Comparative Effectiveness Research, click here to view.
A Real-World Approach to Evidence-Based Medicine in General Practice: A Competency Framework Derived from a Systematic Review and Delphi Process, click here to view.
Comparative Effectiveness of Prostate Cancer Treatments for Patient-Centered Outcomes: A Systematic Review and Meta-Analysis (PRISMA Compliant), click here to view.
11. AHRQ Effective Program Updates
Drug Therapy for Early Rheumatoid Arthritis in Adults – An Update -- Research Protocol, click here to view.
Psychological and Pharmacological Treatments for Adults with Posttraumatic Stress Disorder (PTSD): A Systematic Review Update -- Research Protocol, click here to view
Tympanostomy Tubes in Children with Otitis Media -- Final Report, click here to view
Treatment of Osteoarthritis of the Knee: An Update Review -- Final Report, click here to view.
Assessment Tools for Palliative Care -- Final Report, click here to view.
Noninvasive, Nonpharmacological Treatment for Chronic Pain, click here to view.
The Role of Immunotherapy in the Treatment of Asthma, click here to view
Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy -- Final Report, click here to view.
Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma, clickhere to view.
Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia -- Final Report, click here to view
First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update -- Final Report, click here to view.
Strategies for Improving the Lives of Women Aged 40 and Above Living With HIV/AIDS -- Disposition of Comments, click here to view.
Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review -- Research Protocol, click here to view.
